Target Safety Assessment & Intelligence
Metisox combines a proprietary knowledge base with scientific expertise to assess potential target safety liabilities throughout drug discovery and development. We connect evidence across target biology, biological function, genetic findings, animal models, pharmacology and clinical safety data to give your team a clearer picture of potential risks.
Our evidence is precomputed and referenced, helping us deliver assessments in days rather than weeks.
Single targets or multi-target panels. Reports in your format.
Request a TSA assessmentUnderstand the safety profile of your target.
Get an in-depth assessment of a single target, covering its biological function, expression, associated toxicities and potential safety concerns. Our structured, evidence-based report brings together relevant findings and scientific references to help your team evaluate potential liabilities early in drug discovery and development.
Assess multiple targets. Compare risks side by side.
Evaluate a target family, a bispecific or an acquired portfolio within one assessment. Metisox consolidates the available evidence across targets and ranks potential safety risks in a single heat map, including off-target effects and secondary pharmacology.
Compare safety profiles, identify potential liabilities and prioritise further investigation without having to assemble the evidence target by target.
An expert-curated overview of target family biology, protein structure, cellular localisation, ligand information and biological pathways.
mRNA and protein expression across tissues, sequence homology across species, and relevant isoforms, splice variants and genetic polymorphisms.
An evidence-based review of the target’s role across biological processes, organs and pathways, supported by curated scientific literature and interaction networks.
Findings from genetically modified animal models, human and animal diseases, inhibitors and preclinical studies, and clinical trial safety data.
A structured overview of potential safety signals across relevant organ systems, with supporting scientific references.
Our experts interpret the evidence, assess its relevance to target modulation and highlight potential safety liabilities and limitations in the available data.
Automated reports generated from Metisox’s curated, pre-analysed scientific evidence. Access structured target safety information on demand without an individual expert assessment.
A focused target safety assessment reviewed by our experts. Get key findings and scientific interpretation on a shorter timeline.
An in-depth expert assessment of target safety. Our toxicologists and molecular biologists evaluate the available evidence, interpret potential liabilities and deliver a comprehensive report tailored to your needs.
All formats are available for single targets or multi-target panels, with reports adapted to your preferred format.
“We’ve worked with several providers, but Metisox’s reports are easier to work with. The structure and references are better, and the findings are immediately actionable. We can take the report and get to work.”
Metisox does the heavy lifting: connecting and evaluating scientific evidence so your team can focus on the findings and the decisions ahead.
Request a TSA assessment